Charcot-Marie-Tooth disease is an inherited, genetic condition. It occurs when there are mutations in the genes that affect the nerves in your feet, legs, hands and arms.
Sometimes, these mutations damage the nerves. Other mutations damage the myelin sheath, the protective coating that surrounds the nerve. Both cause weaker messages traveling between your extremities and brain.
That means some of the muscles in your feet may not receive your brain's signal to contract, so you're more likely to trip and fall. And your brain may not receive pain messages from your feet, so if you've rubbed a blister on your toe, for example, it may get infected without your realizing it.