Disease: Milk allergy

    Overview

    Milk allergy is an abnormal response by the body's immune system to milk and products containing milk. It's one of the most common food allergies in children. Cow's milk is the usual cause of milk allergy, but milk from sheep, goats, buffalo and other mammals also can cause a reaction.

    An allergic reaction usually occurs soon after you or your child consumes milk. Signs and symptoms of milk allergy range from mild to severe and can include wheezing, vomiting, hives and digestive problems. Milk allergy can also cause anaphylaxis — a severe, life-threatening reaction.

    Avoiding milk and milk products is the primary treatment for milk allergy. Fortunately, most children outgrow milk allergy. Those who don't outgrow it may need to continue to avoid milk products.

    Source: http://www.mayoclinic.com

    Symptoms

    Milk allergy symptoms, which differ from person to person, occur a few minutes to a few hours after you or your child drinks milk or eats milk products.

    Immediate signs and symptoms of milk allergy might include:

    • Hives
    • Wheezing
    • Itching or tingling feeling around the lips or mouth
    • Swelling of the lips, tongue or throat
    • Coughing or shortness of breath
    • Vomiting

    Signs and symptoms that may take more time to develop include:

    • Loose stools or diarrhea, which may contain blood
    • Abdominal cramps
    • Runny nose
    • Watery eyes
    • Colic, in babies

    Milk allergy or milk intolerance?

    A true milk allergy differs from milk protein intolerance and lactose intolerance. Unlike milk allergy, intolerance doesn't involve the immune system. Milk intolerance requires different treatment from true milk allergy.

    Common signs and symptoms of milk protein intolerance or lactose intolerance include digestive problems, such as bloating, gas or diarrhea, after consuming milk or products containing milk.

    Anaphylaxis

    Milk allergy can cause anaphylaxis, a life-threatening reaction that narrows the airways and can block breathing. Milk is the third most common food — after peanuts and tree nuts — to cause anaphylaxis.

    If you or your child has a reaction to milk, tell your doctor, no matter how mild the reaction. Tests can help confirm milk allergy, so you can avoid future and potentially worse reactions.

    Anaphylaxis is a medical emergency and requires treatment with an epinephrine (adrenaline) shot (EpiPen, Adrenaclick, others) and a trip to the emergency room. Signs and symptoms start soon after milk consumption and can include:

    • Constriction of airways, including a swollen throat that makes it difficult to breathe
    • Facial flushing
    • Itching
    • Shock, with a marked drop in blood pressure

    When to see doctor

    See your doctor or an allergist if you or your child experiences milk allergy symptoms shortly after consuming milk. If possible, see your doctor during the allergic reaction to help the doctor make a diagnosis. Seek emergency treatment if you or your child develops signs or symptoms of anaphylaxis.

    Source: http://www.mayoclinic.com

    Causes

    All true food allergies are caused by an immune system malfunction. If you have milk allergy, your immune system identifies certain milk proteins as harmful, triggering the production of immunoglobulin E (IgE) antibodies to neutralize the protein (allergen). The next time you come in contact with these proteins, IgE antibodies recognize them and signal your immune system to release histamine and other chemicals, causing a range of allergic signs and symptoms.

    There are two main proteins in cow's milk that can cause an allergic reaction:

    • Casein, found in the solid part (curd) of milk that curdles
    • Whey, found in the liquid part of milk that remains after milk curdles

    You or your child may be allergic to only one milk protein or to both. These proteins may be hard to avoid because they're also in some processed foods. And most people who react to cow's milk will react to sheep's, goat's and buffalo's milk. Less commonly, people allergic to cow's milk are also allergic to soy milk.

    Food protein-induced enterocolitis syndrome (FPIES)

    A food allergen can also cause what's sometimes called a delayed food allergy. Although any food can be a trigger, milk is one of the most common. The reaction, commonly vomiting and diarrhea, usually occurs within hours after eating the trigger rather than within minutes.

    Unlike some food allergies, FPIES usually resolves over time. As with milk allergy, preventing an FPIES reaction involves avoiding milk and milk products.

    Source: http://www.mayoclinic.com

    Diagnosis

    When food causes an allergic reaction, it isn't always easy to pinpoint what food is to blame. To evaluate whether you or your child has milk allergy, your doctor may:

    • Ask detailed questions about signs and symptoms
    • Perform a physical exam
    • Have you keep a detailed diary of the foods you or your child eats
    • Have you eliminate milk from your diet or your child's diet (elimination diet) — and then have you add back the food to see if it causes a reaction

    He or she may also recommend one or both of the following tests:

    • Skin test. In this test, your skin is pricked and exposed to small amounts of the proteins found in milk. If you're allergic, you'll likely develop a raised bump (hive) at the test location on your skin. Allergy specialists usually are best equipped to perform and interpret allergy skin tests. Keep in mind that this type of test isn't completely accurate for detecting milk allergy.
    • Blood test. A blood test can measure your immune system's response to milk by measuring the amount of immunoglobulin E (IgE) antibodies in your blood. But this test isn't completely accurate in identifying a milk allergy.

    If your examination and test results can't confirm milk allergy, your doctor might administer an oral challenge, in which you are fed different foods that may or may not contain milk in increasing amounts to see if you react to the ones that contain milk. It's a good idea to have allergy tests administered by an allergist who's been trained to manage serious reactions.

    If your doctor suspects that your symptoms are caused by something other than a food allergy, you may need other tests to identify — or rule out — other medical problems.

    Source: http://www.mayoclinic.com

    Complications

    Children who are allergic to milk are more likely to develop certain other health problems, including:

    • Allergies to other foods — such as eggs, soy, peanuts or even beef
    • Hay fever — a common reaction to pet dander, dust mites, grass pollen and other substances

    Source: http://www.mayoclinic.com

    Prevention

    There's no sure way to prevent a food allergy, but you can prevent reactions by avoiding the food that causes them. If you know you or your child is allergic to milk, avoid milk and milk products.

    Read food labels carefully. Look for casein, a milk derivative, which can be found in some unexpected places, such as in some canned tuna, sausage or nondairy products. Question ingredients when ordering in restaurants.

    Sources of milk

    Obvious sources of allergy-causing milk proteins are found in dairy products, including:

    • Whole milk, low-fat milk, skim milk, buttermilk
    • Butter
    • Yogurt
    • Ice cream, gelato
    • Cheese and anything that contains cheese
    • Half-and-half

    Milk can be harder to identify when it's used as an ingredient in processed foods, including baked goods and processed meats. Hidden sources of milk include:

    • Whey
    • Casein
    • Ingredients spelled with the prefix "lact" — such as lactose and lactate
    • Candies, such as chocolate, nougat and caramel
    • Protein powders
    • Artificial butter flavor
    • Artificial cheese flavor
    • Hydrolysates

    Even if a food is labeled "milk-free" or "nondairy," it may contain allergy-causing milk proteins — so you have to read the label carefully. When in doubt, contact the manufacturer to be sure a product doesn't contain milk ingredients.

    When eating out, ask how foods have been prepared. Does your steak have melted butter on it? Was your seafood dipped in milk before cooking?

    If you're at risk of a serious allergic reaction, talk with your doctor about carrying and using emergency epinephrine (adrenaline). If you have already had a severe reaction, wear a medical alert bracelet or necklace that lets others know you have a food allergy.

    Milk alternatives for infants

    In children who are allergic to milk, breast-feeding and the use of hypoallergenic formula can prevent allergic reactions.

    • Breast-feeding is the best source of nutrition for your infant. Breast-feeding for as long as possible is recommended, especially if your infant is at high risk of developing milk allergy.
    • Hypoallergenic formulas are produced by using enzymes to break down (hydrolyze) milk proteins, such as casein or whey. Further processing can include heat and filtering. Depending on their level of processing, products are classified as either partially or extensively hydrolyzed. Or they may also be called elemental formulas.

      Some hypoallergenic formulas aren't milk based, but instead contain amino acids. Besides extensively hydrolyzed products, amino-acid-based formulas are the least likely to cause an allergic reaction.

    • Soy-based formulas are based on soy protein instead of milk. Soy formulas are fortified to be nutritionally complete — but, unfortunately, some children with a milk allergy also develop an allergy to soy.

    If you're breast-feeding and your child is allergic to milk, cow's milk proteins passed through your breast milk may cause an allergic reaction. You may need to exclude from your diet all products that contain milk. Talk to your doctor if you know — or suspect — that your child has milk allergy and develops allergy signs and symptoms after breast-feeding.

    If you or your child is on a milk-free diet, your doctor or dietitian can help you plan nutritionally balanced meals. You or your child may need to take supplements to replace calcium and nutrients found in milk, such as vitamin D and riboflavin.

    Source: http://www.mayoclinic.com

    Coping and support

    Having a serious allergy or being the parent of a child with a potentially life-threatening allergy can be stressful. Talking to others in similar situations can be helpful. Besides offering support and encouragement, they may also provide useful coping tips, such as how to deal effectively with school officials to ensure your child's medical needs are met. Ask your doctor if there are any support groups in your area, or contact the Asthma and Allergy Foundation of America.

    Source: http://www.mayoclinic.com

    Risk factors

    Certain factors may increase the risk of developing milk allergy:

    • Other allergies. Many children allergic to milk also have other allergies. Milk allergy may develop before other allergies.
    • Atopic dermatitis. Children who have atopic dermatitis — a common, chronic inflammation of the skin — are much more likely to develop a food allergy.
    • Family history. A person's risk of a food allergy increases if one or both parents have a food allergy or another type of allergy or allergic disease — such as hay fever, asthma, hives or eczema.
    • Age. Milk allergy is more common in children. As they age, their digestive systems mature, and their bodies are less likely to react to milk.

    Source: http://www.mayoclinic.com

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